Found 3 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM50378944'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 126nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 126nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Universitaet Des Saarlandes Campus Saarbruecken
US Patent
Affinity DataIC50: 181nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair