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Found 16 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM50010686'
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1-like receptor in porcine striata homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  33nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  33nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]-SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  35.7nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  100nMAssay Description:In vitro binding affinity against Dopamine receptor D1 like from rat caudate membrane using [125I]-SCH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataKi:  1.20E+3nMAssay Description:Affinity towards Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataIC50:  5.60nMAssay Description:Tested for its affinity towards Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataIC50:  7.15nMAssay Description:Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataIC50:  149nMAssay Description:Tested for its affinity towards Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataEC50:  14nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataEC50:  30nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataEC50:  19nMAssay Description:Activity at human dopamine D1 receptor expressed in HEK293 cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataEC50:  14nMAssay Description:Binding affinity to Dopamine receptor D1 by using radioligand [125I]-SCH-23982 in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Quimique C£A.

Curated by ChEMBL
LigandPNGBDBM50010686((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed