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Found 8 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM50431078'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  10nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  10nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  10nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails US Patent