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Found 3 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 1' and Ligand = 'BDBM50457746'
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457746(CHEMBL4208004)
Affinity DataIC50:  32nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457746(CHEMBL4208004)
Affinity DataIC50:  32nMAssay Description:Inhibition of human DNMT1 enzyme using polydeoxy-inosine polydeoxy-cytosine DNA as substrate incubated for 15 mins in presence of SAM by TR-FRET assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457746(CHEMBL4208004)
Affinity DataIC50:  32nMAssay Description:Inhibition of DNMT1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed