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Found 1 Enz. Inhib. hit(s) with Target = 'DNA ligase 1' and Ligand = 'BDBM23057'
TargetDNA ligase 1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM23057(alpha-ketooxazole, 5cc | methyl 4-{7-oxo-7-[5-(pyr...)
Affinity DataKi:  1.5nM ΔG°:  -49.9kJ/mole IC50:  0.240nMpH: 9.0 T: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed