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Found 1 Enz. Inhib. hit(s) with Target = 'DNA ligase 1' and Ligand = 'BDBM23077'
TargetDNA ligase 1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM23077(3-[4-(phenylsulfanyl)phenyl]-1-[5-(pyridin-2-yl)-1...)
Affinity DataKi:  2.20nM ΔG°:  -49.4kJ/mole IC50:  2nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed