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Found 2 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50045362'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045362((20RS)-7-ethyl-8,11-dioxo-7,8,11,13-tetrahydro-10H...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045362((20RS)-7-ethyl-8,11-dioxo-7,8,11,13-tetrahydro-10H...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed