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Found 3 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP' and Ligand = 'BDBM50316637'
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50316637((2S)-2-(methylamino)-N-[(2S,5S,11S,20S,23S,29S)-29...)
Affinity DataIC50:  0.430nMAssay Description:Binding affinity to XIAP linker BIR2-BIR3 domain site 1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50316637((2S)-2-(methylamino)-N-[(2S,5S,11S,20S,23S,29S)-29...)
Affinity DataIC50:  28nMAssay Description:Binding affinity to XIAP linker BIR2-BIR3 domain site 2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50316637((2S)-2-(methylamino)-N-[(2S,5S,11S,20S,23S,29S)-29...)
Affinity DataIC50:  3.20E+3nMAssay Description:Binding affinity to XIAP linker BIR2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed