Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Endothelial PAS domain-containing protein 1' and Ligand = 'BDBM282584'
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics

Curated by ChEMBL
LigandPNGBDBM282584(4-Chloro-5-(3-chloro-5-fluorophenoxy)-2,2-difluoro...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to His-tagged HIF-2alpha PAS-B domain (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
Peloton Therapeutics

Curated by ChEMBL
LigandPNGBDBM282584(4-Chloro-5-(3-chloro-5-fluorophenoxy)-2,2-difluoro...)
Affinity DataEC50:  110nMAssay Description:Antagonist activity at HIF-2alpha in human 786-O cells co-expressing HIF responsive element after 24 hrs by ONE-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed