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Found 2 Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM50444139'
TargetEndothelial lipase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444139(CHEMBL3093395)
Affinity DataIC50:  214nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444139(CHEMBL3093395)
Affinity DataIC50:  330nMAssay Description:Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed