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Found 3 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50329839'
TargetEndothelin-1 receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50329839(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [125I]ET1 from ETA receptor expressed in african green monkey CCL-81 cells monolayerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50329839(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at ETB receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50329839(3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol...)
Affinity DataIC50:  4.20nMAssay Description:Antagonist activity at ETA receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed