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Found 2 Enz. Inhib. hit(s) with Target = 'Farnesyl pyrophosphate synthase' and Ligand = 'BDBM50428313'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428313(CHEMBL2338377)
Affinity DataIC50:  43nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428313(CHEMBL2338377)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed