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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein/Non-structural protein 4A' and Ligand = 'BDBM50141202'
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141202(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataKi: <220nMAssay Description:Binding inhibition of hepatitis C virus NS3.4A protease 2 using p-nitroaniline assay (pNA); <0.2 (0.15)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141202(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid (S)-...)
Affinity DataIC50:  420nMAssay Description:Binding inhibition of hepatitis C virus NS3.4A protease 2 using a reverse phase HPLC based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed