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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM123412'
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123412(US8741926, 57 | US8754106, 57)
Affinity DataKi:  0.300nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123412(US8741926, 57 | US8754106, 57)
Affinity DataKi:  0.300nM ΔG°:  -55.3kJ/molepH: 7.5 T: 2°CAssay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
In DepthDetails US Patent