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Found 10 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50111469'
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  58nMAssay Description:Inhibition of HRV Protease 3CP (serotype 14).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  4nMAssay Description:Inhibition of Rhinovirus A89 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  30nMAssay Description:Inhibition of Rhinovirus B14 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  490nMAssay Description:Inhibition of Rhinovirus A08 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human enterovirus 71 (strain BrCr) (Ev 71))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  167nMAssay Description:Inhibition of Rhinovirus B70 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  15nMAssay Description:Inhibition of Rhinovirus A28 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50: >1.28E+5nMAssay Description:Inhibition of Rhinovirus B42 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  15nMAssay Description:Inhibition of Rhinovirus A02 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus 1A)
Umr 7273 Cnrs

Curated by ChEMBL
LigandPNGBDBM50111469(3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propox...)
Affinity DataEC50:  11nMAssay Description:Inhibition of Rhinovirus A85 capsid infected in human HeLa Rh cells assessed as reduction in virus-induced cytopathic effect after 3 days by MTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed