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Found 3 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl pyrophosphate synthase' and Ligand = 'BDBM25284'
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)
Affinity DataKi:  70nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute Of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)
Affinity DataIC50:  2.69E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed