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Found 4 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50416868'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50:  6.31nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human HeLa cells assessed as inhibition of TPA-induced coll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataIC50:  19.9nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced IL-8...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416868(CHEMBL1257453)
Affinity DataEC50:  79.4nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed