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Found 8 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50416869'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  3.16nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human HeLa cells assessed as inhibition of TPA-induced coll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  5nMAssay Description:Binding affinity to recombinant human glucocorticoid receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  5nMAssay Description:Binding affinity to recombinant human glucocorticoid receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  5.01nMAssay Description:Transrepression activity at glucocorticoid receptor-mediated antiinflammatory activity in human THP1 cells assessed as inhibition of LPS-induced IL-8...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  5.01nMAssay Description:Transrepression activity at glucocorticoid receptorin human HeLa cells assessed as inhibition of TPA-induced collagenase promoter activity by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  6.30nMAssay Description:Binding affinity to recombinant human glucocorticoid receptor expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataIC50:  6.31nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50416869(CHEMBL1257572)
Affinity DataEC50:  12.6nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed