Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, kainate 1' and Ligand = 'BDBM50185318'
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
University Walk
Curated by ChEMBL
University Walk
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 105nMAssay Description:Activity at native GLUK5 kainate receptor assessed as antagonism of kainite-induced depolarization of neonatal anaesthetised rat dorsal root fibresMore data for this Ligand-Target Pair