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Found 3 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50086621'
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086621(CHEMBL141539 | Trifluoro-acetate2-{2-[7-chloro-3-(...)
Affinity DataIC50:  320nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086621(CHEMBL141539 | Trifluoro-acetate2-{2-[7-chloro-3-(...)
Affinity DataIC50:  775nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086621(CHEMBL141539 | Trifluoro-acetate2-{2-[7-chloro-3-(...)
Affinity DataIC50: >1.28E+3nMAssay Description:In vitro inhibition of GnRH stimulated release of luteinizing hormone from the rat primary pituitary cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed