Found 5 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50359981' TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrsMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 321nMAssay Description:Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 811nMAssay Description:Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TPR-fused MET-mediated mouse BA/F3 cell proliferation after 48 hrs by cell titre blue based spectrophotometryMore data for this Ligand-Target Pair
