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Found 2 Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM50054057'
TargetHexokinase-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50054057(CHEMBL3319544)
Affinity DataIC50:  6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50054057(CHEMBL3319544)
Affinity DataEC50:  565nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed