Found 3 Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B' and Ligand = 'BDBM50594973' TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Shaoxing University
Curated by ChEMBL
Shaoxing University
Curated by ChEMBL
Affinity DataIC50: <0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Shaoxing University
Curated by ChEMBL
Shaoxing University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at AT1 receptor assessed inhibition of angiotensin-2-induced contraction of rabbit thoracic aortic ringsMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Shaoxing University
Curated by ChEMBL
Shaoxing University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonistic affinity tested against isolated Rat Thoracic Aorta Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
