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Found 2 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM197114'
TargetHistamine H3 receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM197114(US9216182, 1.60)
Affinity DataKi:  0.100nMAssay Description:The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM197114(US9216182, 1.60)
Affinity DataKi:  1.40nMpH: 7.5Assay Description:The affinity of compounds of the invention to the H3 receptor can be assessed by measuring displacement of binding of the radioligand [3H]-N-α-Methy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent