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Found 3 Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM22862'
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataKi:  794nM ΔG°:  -36.2kJ/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

LigandPNGBDBM22862(2-(2-methyl-1H-imidazol-4-yl)ethan-1-amine | 2-Met...)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2 by steady-state GTPase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed