TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataEC50: 0.560nMAssay Description:Agonist activity at human histamine H4 receptor in SK-N-MC cells assessed as forskolin-stimulated cAMP release preincubated for 10 mins before forsko...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataEC50: 39nMAssay Description:Intrinsic activity at mouse histamine H4 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP responsive elemen...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataEC50: 548nMAssay Description:Displacement of [3H]histamine from mouse recombinant histamine H4 receptorMore data for this Ligand-Target Pair