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Found 4 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50248473'
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248473(CHEMBL523646 | N-hydroxy-3-(1-(3-(2-oxopyrrolidin-...)
Affinity DataIC50:  195nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248473(CHEMBL523646 | N-hydroxy-3-(1-(3-(2-oxopyrrolidin-...)
Affinity DataIC50:  195nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248473(CHEMBL523646 | N-hydroxy-3-(1-(3-(2-oxopyrrolidin-...)
Affinity DataIC50:  195nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248473(CHEMBL523646 | N-hydroxy-3-(1-(3-(2-oxopyrrolidin-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed