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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50207561'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Queensland

LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  5.00E+3nMpH: 8.0Assay Description:Fluorescence readings were carried out on a CytofluorR Series 4000 fluorescence multiwell plate reader (Perspective Biosystems). Stock solutions of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Queensland

LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged HDAC6 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Queensland

LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293 cells using Lys-Ac-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed