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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM120996'
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM120996(US8716285, 53)
Affinity DataIC50:  470nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM120996(US8716285, 53)
Affinity DataIC50:  470nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent