Found 3 Enz. Inhib. hit(s) with Target = 'Histone-arginine methyltransferase CARM1' and Ligand = 'BDBM27659'
Affinity DataIC50: 80nMpH: 9.0 T: 2°CAssay Description:Histone H3 is used as the substrate for CARM-1 enzyme, and the methylation is monitored using tritiated S-Adenosyl-Methionine (SAM) as a methyl donor...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human GST-tagged CARM1 by methylation assayMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair