Found 3 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT2' and Ligand = 'BDBM50281305' TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Non-competitive inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of 2 to 640 uM SAM by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Competitive inhibition of human G9a using 40 to 2560 nM biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
