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Found 2 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50517807'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Xihua University

Curated by ChEMBL
LigandPNGBDBM50517807(CHEMBL4570374)
Affinity DataIC50:  740nMAssay Description:Inhibition of human IDO1 expressed in Escherichia coli using L-tryptophan as substrate after 1 hr by UV absorption analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Xihua University

Curated by ChEMBL
LigandPNGBDBM50517807(CHEMBL4570374)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma-induced human HeLa cells assessed as reduction in L-kynurenine level after 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed