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Found 2 Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50158091'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50158091(CHEMBL3780331 | US10858316, Compound 3f)
Affinity DataKi:  2.10E+4nMAssay Description:Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50158091(CHEMBL3780331 | US10858316, Compound 3f)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed