Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-4/beta-1' and Ligand = 'BDBM50105400'
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105400((S)-2-{[(S)-2-(3,4-Dimethoxy-benzenesulfonyl)-1,2,...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of [125I]VCAM-Ig binding to Alpha-4 beta-1 (VLA-4) of Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105400((S)-2-{[(S)-2-(3,4-Dimethoxy-benzenesulfonyl)-1,2,...)
Affinity DataIC50:  0.530nMAssay Description:Antagonist activity at alpha4beta1 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105400((S)-2-{[(S)-2-(3,4-Dimethoxy-benzenesulfonyl)-1,2,...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity against alpha-4 beta-1 receptor (VLA-4) in human RPMI-8866 cells using [125I]-VCAM-Ig ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105400((S)-2-{[(S)-2-(3,4-Dimethoxy-benzenesulfonyl)-1,2,...)
Affinity DataIC50:  58nMAssay Description:Inhibition of [125I]VCAM-Ig binding to VLA-4 integrin of human Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed