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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Interleukin-1 beta' and Ligand = 'BDBM398220'
Target
Interleukin-1 beta
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM398220
(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-((1-...)
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Affinity Data
IC50: <10nM
Assay Description:
The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...
More data for this Ligand-Target Pair
Target Info
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MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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Ligand Info
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In Depth
Details
US Patent
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