Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Interstitial collagenase' and Ligand = 'BDBM11548'
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11548(CHEMBL100570 | N-hydroxy-2-[(4-methoxy-1,1-bipheny...)
Affinity DataKi: >4.95E+3nM ΔG°: >-30.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11548(CHEMBL100570 | N-hydroxy-2-[(4-methoxy-1,1-bipheny...)
Affinity DataKi:  4.95E+3nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11548(CHEMBL100570 | N-hydroxy-2-[(4-methoxy-1,1-bipheny...)
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed