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Found 1 Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM619957'
TargetKallikrein-1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM619957(6-(2-((3S,8aR)-7-(3-Chloro-2-fluoro-6-(1H-tetrazol...)
Affinity DataIC50:  0.800nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of human plasma kallikrein. The peptide substrate, Z-Gly-Pro-Arg-AMC (Pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent