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Found 8 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50135806'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0500nMAssay Description:Inhibitory activity against Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes was determined using [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataEC50:  0.850nMAssay Description:Inhibitory activity in stimulating [35S]-GTP-gamma S binding mediated by the Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed