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Found 2 Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1' and Ligand = 'BDBM50200466'
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200466(CHEMBL3913014)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) interaction with Nrf2 assessed as displacement of FITC-betaAla-DEETGEF-OH from Keap1 Kelch domain b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200466(CHEMBL3913014)
Affinity DataKd:  10nMAssay Description:Binding affinity to Keap1 (unknown origin) Kelch domain by ITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed