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Found 2 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM24105'
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24105(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli...)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24105(7,8-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli...)
Affinity DataIC50:  8.33E+3nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed