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Found 3 Enz. Inhib. hit(s) with Target = 'Lethal factor' and Ligand = 'BDBM8503'
TargetLethal factor(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM8503((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataKi:  24nMAssay Description:Competitive inhibition of Bacillus anthracis recombinant lethal factor expressed in Escherichia coli by linear double-reciprocal plot analysisMore data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM8503((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataKi:  24nMAssay Description:Binding affinity to Bacillus anthracis lethal factor assessed as inhibition constantMore data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM8503((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  54nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair