Found 3 Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM482159' TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Neurodegeneration Dpu
Curated by ChEMBL
Neurodegeneration Dpu
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of LRRK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Neurodegeneration Dpu
Curated by ChEMBL
Neurodegeneration Dpu
Curated by ChEMBL
Affinity DataIC50: 10.9nMAssay Description:Inhibition of recombinant His6-Tev-tagged LRRK2 expressed in baculovirus assessed as inhibition of LRRKtide phospohorylation by HTRF assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Neurodegeneration Dpu
Curated by ChEMBL
Neurodegeneration Dpu
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of full length wild-type LRRK2 (unknown origin) using biotinylated ezrin/radaxin/meosin peptide as substrate measured after 1 hrMore data for this Ligand-Target Pair
