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Found 3 Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM50508756'
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508756(CHEMBL4549553 | US11312713, Example 1)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (unknown origin) expressed in baculovirus expression system using fluorescein-labeled LRRKtide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508756(CHEMBL4549553 | US11312713, Example 1)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant wild-type GST-tagged LRRK2 (unknown origin) expressed in baculovirus expression system using fluorescein-labeled LRRKtide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508756(CHEMBL4549553 | US11312713, Example 1)
Affinity DataIC50:  10.2nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent