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Found 5 Enz. Inhib. hit(s) with Target = 'Leukotriene A-4 hydrolase' and Ligand = 'BDBM50575488'
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of LTA4H in human PBMC assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed by ion...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50:  53nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50:  167nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 15 mins follow...More data for this Ligand-Target Pair