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Found
1
Enz. Inhib. hit(s) with Target = 'Leukotriene C4 synthase' and Ligand = 'BDBM223259'
Target
Leukotriene C4 synthase
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM223259
(2-(5-((Cyclopropylmethyl)(4-(trifluoromethyl)napht...)
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Affinity Data
IC50: 19nM
pH: 7.8
Assay Description:
In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...
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Target Info
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Ligand Info
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