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Found 3 Enz. Inhib. hit(s) with Target = 'Liver carboxylesterase 1' and Ligand = 'BDBM50130915'
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  140nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CE1 using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition and measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  210nMAssay Description:Inhibition of CE1 in human liver microsomes using D-Luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed