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Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50434486'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434486(CHEMBL2385548)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434486(CHEMBL2385548)
Affinity DataEC50:  138nMAssay Description:Inhibition of MK2 in human THP1 cells assessed as phosphorylation of HSP27 at serine78 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed