Found 2 Enz. Inhib. hit(s) with Target = 'Mannan-binding lectin serine protease 1' and Ligand = 'BDBM50462102'
TargetMannan-binding lectin serine protease 1(Homo sapiens)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibition of MASP-1 (unknown origin) using Z-L-LysSBzl hydrochloride as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
TargetMannan-binding lectin serine protease 1(Homo sapiens)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of MASP-1-mediated C3 deposition in human serum after 30 mins by ELISAMore data for this Ligand-Target Pair