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Found 5 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50034501'
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataEC50:  6.00E+3nMAssay Description:Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataEC50:  4.40E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataEC50:  4.30E+4nMAssay Description:Activity at rat cloned mGluR1a expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataEC50:  6.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1c in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Cns Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed