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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50258225'
TargetMetabotropic glutamate receptor 1(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50258225(2,7-difluoro-N-(oxazol-2-yl)-9H-xanthene-9-carboxa...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in CHO cells assessed as reversal of glutamate-activated K+ currents by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50258225(2,7-difluoro-N-(oxazol-2-yl)-9H-xanthene-9-carboxa...)
Affinity DataEC50:  124nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in HEK293 cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed